Plasma Lipoperoxide Levels in Cold- and Heat-Acclimated Rats

Abstract

Blood lipoperoxide (LP), free fatty acids (FFA) and β-hydroxybutyrate levels were measured in the warm controls (WA), cold-acclimated (CA) and heat-acclimated (HA) rats. In CA of 2 wk-cold exposure FFA level was higher than in WA, but no difference was observed between WA and CA of 4 wk-cold exposure. Beta-hydroxy butyrate showed the similar changes to that of FFA. LP did not show any significant changes during cold acclimation.
In HA, FFA and LP levels were significantly lower during heat acclimation as compared with those in WA. Beta-hydroxybutyrate did not change during heat acclimation. The results suggest that the peripheral pathological changes and the shortened life-span previously reported for coldacclimated animals are not induced by greater formation rate of lipoperoxides.