SEISAN KENKYU
Online ISSN : 1881-2058
Print ISSN : 0037-105X
ISSN-L : 0037-105X
Research Review
Asymmetric synthesis in aqueous media using highly functionalized resin-supported peptide catalyst
Kengo AKAGAWAKazuaki KUDO
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JOURNAL FREE ACCESS

2010 Volume 62 Issue 3 Pages 219-224

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Abstract
Efficient systems for catalytic asymmetric syntheses in aqueous media have been developed by using amphiphilic-resin-supported hydrophobic peptides having terminal prolyl groups. The supported peptide catalysts can be easily synthesized through the conventional solid-phase method, and have some merits such as reusability, applicability to sequential reactions, and facility for optimizing peptide sequences. The catalytic systems in aqueous media with the supported peptides are expected to provide the efficient procedures for the production of chiral fine chemicals.
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© 2010 Institute of Industrial Science The University of Tokyo
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