Abstract
The greatest known risk factor for Alzheimer's disease (AD) is aging. Since AD is a progressive neurodegenerative brain disease, the altered cognitive symptoms in the very early stage of AD involve mild learning, memory or planning problems. Eventually, AD patients will lose their ability to carry out the simplest tasks of daily living when in the later severe stage. Currently, no medical tests are available to diagnose AD conclusively pre-mortem. A large number of studies convincingly demonstrate that the cognitive deficits of AD are possible to detect during a preclinical period spanning several years. In this review, we focus on the early detection of AD with combined psychological and neuropsychological approaches such as functional magnetic resonance imaging (fMRI) and Electroencephalogram (EEG).
