Bactericidal Effects of Disinfectants Against Methicillin-Resistant Staphylococci : (2) Efficacy of Germicidal Agents Used on Hospital Equipment

Abstract

We investigated the minimum inhibitory concentrations (MIC) of 5 germicidal agents used on hospital equipment to 16 methicillin-resistant staphylococci (MRS) isolated from Osaka Dental University Hospital. The MIC for sodium hypochlorite, benzalkonium chloride, glutaraldehyde and alkyldiaminoethylglycine against all MRS strains tested were within concentrations recommended for disinfection. However, the MIC of chlorlhexidine gluconate against two of the MRS strains tested indicated the need for an elevated concentration for disinfection.
      These results suggest that all the disinfectants except chlorhexidine gluconate are appropriate for preventing nosocomial MRS infections in Osaka Dental University Hospital.