Experimental studies on alveolar bone formation with α-TCP collagen material

Abstract

Excessive alveolar bone resorption is an obstacle to denture treatment. We evaluated how evaluated how α-TCP with collagen sponge and α-TCP processed with tannic acid improvws bone configuration. Defects were artificially made in the alveolar bone of Japanese monkeys and were filled with the above materials. At 2, 4, and 8weeks after placement of the material, microvascular casts were made for observation by scanning electron microscope. α-TCP processed with tannic acid promoted dense capollaries and markedly enhanced bone healing. The results indicated that application of this material in bone defects should be useful in promoting alveolar bone formation for denture treatment.