Effects of experimental occulusal interference on dopamine release in rat prefrontal cortex

Abstract

In order to determine if disturbances in mastication resulting from occlusal dysfunction affect mental stress, I created experimental occlusal interferences in rats and monitored dopamine release in their prefrontal cortex.Extracellular fluid dopamine volume in the prefrontal cortex was measured by the brain microdialysis method.When the animals with occlusal interferences were fed cubed food, there was an increase in dopamine volume in the prefrontal cortex.Experimental occlusal interference affected dopamine metabolism in the rat prefrontal cortex when the animals were fed, clearly inducing a strong stress reaction.