Periodontal therapy with local delivery of antibiotics : Part 1 Observation at Osaka Dental University

Abstract

The topical application of antibiotics in periodontal pockets has been widely used for treatment of periodontal disease. However, there are no clear guidelines as to the ideal frequency and duration of application. We clinically examined the effects of administering Periocline^【○!R】in combination with scaling and root planing (group B) as compared with scaling and root planing alone (group A). We found that with the exception of the plaque index, there was more improvement in group B than in group A throughout the observation period.