2 Effect of combinations of three precious alloys on dissolution and cell viability using a dynamic extraction

Abstract

We examined the effect of similar and dissimilar combinations of three precious dental alloys under dynamic extraction on metal release and cell viability. The amount of metal measured by inductively coupled plasma spectrometry in extracts of dissimilar combinations was greater than that of similar combinations. Only Cu and Zn were detected in the filtrates. Cell viability, as evaluated by L-929 mouse fibroblasts, of the dissimilar combinations was lower than that of the similar combinations. These findings indicate that dynamic contact between two alloys influences metal release and cellular response.