4 Quantitative light-induced fluorescence clinical study on how fluoride dentifrice affects the progression of white spot lesions

Abstract

We examined the effect of fluoride dentifrice on remineralization of white spot lesions by using quantitative light-induced fluorescence (QLF). The study was done on 129 subjects who had given their informed consent. Sixty-five of the subjects were randomly allocated to a group that brushed with 950 ppm fluoride dentifrice, while 64 others used a dentifrice without fluoride. The subjects brushed their teeth twice a day with their assigned dentifrice for one year. The remineralization effect of the two dentifrices was evaluated by three QLF parameters : mineral loss measured by ΔQ (% mm^2), lesion area measured by S(mm^2), and maximum lesion depth measured by ΔMax (%). These three parameters were recorded at three, six, and twelve month recalls after the baseline examination. We concluded that the fluoride dentifrice improved remineralization of the clinical white spot lesions.