6 Experimental study of the bone defect repair process with different sizes of β-tricalcium phosphate granules

Abstract

We used β-tricalcium phosphate (β-TCP) granules to repair bone defects in crab-eating monkeys, and observed the results with LM, SEM and micro-computed tomography. During the early stages of the repair process, osteogenesis progressed more rapidly in the group treated with the large granule size than in the group treated with the small granule size. However, both experimental groups had nearly the same level of osteogenesis after 12 weeks. Furthermore, at 12 weeks the defects had been repaired in both groups regardless of the granule size.