2015 Volume 78 Issue 1 Pages 25-
Strontium (Sr) ions are often used for treatment of bone disease. However, it is unclear whether they are applicable for cartilage regeneration therapy using adipose-derived stem cells (ADSCs). We demonstrated in this study that the Sr ions contained in a chondrogenic medium (CM) enhanced the chondrogenic differentiation for ADSCs in vitro up to day 14. In addition, the media caused no elevation in osteoblastic, hypertrophic chondrogenic, or adipogenic differentiation. We concluded that Sr supplementation in CM might be useful for preparing ADSCs-derived chondrocytes for chondrogenic regeneration therapy in cleft lip and palate cases.
