2017 Volume 80 Issue 2 Pages 55-66
The initial adhesion of microorganisms to clinically used dental biomaterials is influ enced by physicochemical parameters, such as preadsorption of salivary proteins. The forma tion of biofilms begins with the adhesion of microorganisms. The presence of biofilms is thought to affect the ability of microorganisms to adsorb and accumulate on the surfaces of denture ma terials, facilitating bacterial adhesion and resulting in a greater risk of bacterial infiltration of the denture materials. Many common materials, such as polymers and metal alloys, are currently used in the manufacture of dentures. It is important to quantitatively investigate the adsorption of salivary proteins to denture materials. We fabricated highly stable denture materials as quartz crystal microbalance (QCM) sensors and evaluated the difference in the adsorption behavior to them of different types of bovine salivary proteins. PMMA and Ti QCM sensors were fabricated by spincoating and sputtering onto bare QCM sensors. The amount of salivaryrelated protein on the PMMA QCM sensors was greater than those on the Ti and Au QCM sensors. We found that the PMMA and Ti QCM sensors are useful tools to study the adsorption and desorption of albumin and mutin on denture surfaces. Shika Igaku (J Osaka Odontol Soc) 2017 ;Septem ber ;80(2) : 55-66.