2021 Volume 94 Issue 12 Pages 325-329
IgM antibodies produced by mammalian B lymphocytes are involved in the host’s defense against pathogen and viral infections. IgMs are produced in the early stages of these infections and can be used as an indicator of early diagnosis. While there are many other benefits to using IgM in medical applications, its unstable properties make it impractical as an antibody material. In recent years, the technological environment for IgM purification has been improved, and it is becoming possible to prepare IgM suitable for industrial applications. Here, we introduce the latest topics of IgM purification technology.