Thyroid Eye Disease

Abstract

Thyroid eye disease is an one of autoimmune disease that is developed by hyper-,eu-,and hypothyroid-Graves' disease. Thyrotropin receptor antibodies(TRAb)and thyroid stimulating antibodies(TSAb)are well known as an anti-thyroid autoantibodies, and TSAb is more related to severity and activity of the thyroid eye disease. The treatment of thyroid eye disease is mainly the anti-inflammatory therapy, the normalization of thyroid functions and TRAb for immunological remission. Thyroid eye disease trend to worse in patients with high TRAb levels. MRI is an important examination because it can determine the activity of thyroid eye disease. We present three cases who are progressed the thyroid eye disease before the onset of Graves' disease,developed the thyroid eye disease after isotopetreatment, and relapsedafterthyroidectomy. Although new therapies for the thyroid eye disease have also been verified, the steroid therapy is the mainly treatment for anti-inflammatory and immunosuppression.