Neuro-Ophthalmology Japan
Online ISSN : 2188-2002
Print ISSN : 0289-7024
ISSN-L : 0289-7024
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The Effects and Limitations of Steroid Therapy and Radiation Therapy for Thyroid Eye Disease
Ai Kozaki
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2020 Volume 37 Issue 3 Pages 264-273

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Abstract

 The effects and limitations of anti-inflammatory treatment for thyroid eye disease were investigated. A therapeutic effect was seen in 60-75%of the patients who received steroid pulse therapy alone, in 44-53%who received radiation therapy alone, and in 66%who received a combination of both. Of the cases with diplopia at the first visit, 16.5%finally underwent strabismus surgery. In particular, 30.3%of the patients with diplopia in the primary position required strabismus surgery. For upper eyelid retraction, steroid therapy was effective, and less than 1%of the patients were operated. Further, 22.3%of the patients with dysthyroid optic

neuropathy underwent orbital decompression after anti-inflammatory therapy, and 58.3%of the severe cases with pretreatment visual acuity of less than 0.1 were operated. Some patients with diplopia and dysthyroid optic neuropathy due to thyroid eye disease required surgical treatment owing to the limitations of anti-inflammatory treatment.

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© 2020 The Japanese Neuro-Ophthalmology Society
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