変異KRASを標的とした新たな癌治療時代の現状と展望～癌シグナルから考える耐性メカニズムとそれを克服するコンビネーション治療～

北沢 将人; 小山 誠; 中村 聡; 宮﨑 暁; 本藤 奈緒; 片岡 将宏; 副島 雄二

doi:10.11441/shinshumedj.71.383

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The Current State and Prospects of the New Era of Cancer Treatment Targeting Mutated KRAS : Considering Resistance Mechanisms from Cancer Signaling and Overcoming Them with Combination Therapies

Masato KITAZAWA, Makoto KOYAMA, Satoshi NAKAMURA, Satoru MIYAZAKI, Nao HONDO, Masahiro KATAOKA, Yuji Soejima

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Keywords: KRAS, sotorasib, adagrasib, MRTX1133, combination therapy

JOURNAL FREE ACCESS

2023 Volume 71 Issue 6 Pages 383-392

DOI https://doi.org/10.11441/shinshumedj.71.383

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