Abstract
We had an opportunity to treat two infants affected with refractory otitis media. The patients were hospitalized for treatment of the infectious disease. We isolated BLNAR(β-lactamasenegative ampicillin-resistant Haemophilus influenzae) from these excretes obtained from patients who were successfully treated with CTRX. The MICs of microbes obtained from the two patients were 8 and 4μg/ml to ABPC. The MIC was 0.06 and 0.25μg/ml in response to CTRX. The two infants recovered from the infection in a week. In our hospital, infectious diseases caused by BLNAR account for more than 20% of Haemophilus influenzae infections. The incidence of BLNAR infections may increase in the future.
