Abstract
The patient is a six-year-old boy with Prader-Willi syndrome (PWS). He started GH therapy when he was five years of age. Although he showed mild sleep problems before GH therapy, he did not have upper airway obstruction. Nine months after the initiation of GH therapy, he began to show severe sleep apnea. Otorinolaryngologic study revealed marked enlargement of the adenoid. After adenoidectomy, he showed remarkable improvement in sleep apnea.
Although the causal connection between GH therapy and adenoid enlargement is not clear, in this patient, GH therapy might have been associated with the cause of airway obstruction.
