Abstract
We report an 11-month-old male infant. He was found to have bilateral sensorineural hearing loss on newborn hearing screening. At 9 months of age he developed infantile spasms and was diagnosed as cytomegalovirus (CMV) infection and persistent bilateral hearing loss on auditory brainstem response (ABR). We attempted immunoglobulin therapy for 3 days and gancyclovir therapy for 14 days. After antiviral therapy, urinary excretion of CMV-DNA measured by PCR assay disappeared, and on ABR recordings improvement in the acoustic threshold and reduction of peak latencies were remarkable. Due to severe developmental delay and anticonvulsant therapy, his auditory behavior was hard to investigate.
