Fluctuation Dynamics in Coupled Oscillator Systems of Spontaneously Beating Cultured Cardiac Myocytes

Mitsuru Yoneyama; Koichi Kawahara

doi:10.11499/sicep.2004.0_43_2

SICE Annual Conference 2004

DOI https://doi.org/10.11499/sicep.2004.0_43_2

Conference information

Host: The Society of Instrument and Control Engineers

Co-host: The IEEE Industrial Electronics Society, The IEEE Robotics and Automation Society, The IEEE Control Systems Society, The IEEE Systems, Man and Cybernetics Society, The Instrumentation, Systems, and Automation Society

Fluctuation Dynamics in Coupled Oscillator Systems of Spontaneously Beating Cultured Cardiac Myocytes

*Mitsuru Yoneyama, Koichi Kawahara

Author information

Keywords: cardiac myocyte, fluctuation analysis, scaling

CONFERENCE PROCEEDINGS FREE ACCESS

Pages 43

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Abstract

We report results of experimental and simulation studies on the fluctuation dynamics of interbeat intervals (IBIs) in aggregated systems of spontaneously beating cultured neonatal rat cardiac myocytes. The correlation properties of the IBI fluctuations vary depending on incubation time, which can be reproduced using Bonhoeffer-van der Pol coupled oscillator model with appropriate values of coupling strength among the oscillators.

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