Abstract
A 59-year-old woman noted a nodule on her back in 2002. The nodule was untreated ; it gradually increased in size, so she visited our hospital in March 2007. The tumor size was 4×4×2cm and dome-shape. It was excised with a 1cm surgical margin. Histologically, the central part of the tumor appeared to be compatible with fibrosarcoma, because it contained a dense proliferation of atypical spindle cells arranged in herring-bone-patterns, and the edge of the tumor consisted of dermatofibrosarcoma protuberans (DFSP) composed of uniform spindle-shaped tumor cells in storiform patterns. Immunohistochemical staining of CD34 showed strongly positive in the fibrosarcomatous area and showed positive in the DFSP area. It was diagnosed as fibrosarcomatous variant of DFSP, and wide excision of the tumor including muscle was performed with a 3cm margin from the first operating wound. No local recurrence or metastasis was seen during the follow-up period of 1 year.[Skin Cancer (Japan) 2009 ; 24 : 57-61]
