Abstract
A 66-year-old man presented with a three-month history of swollen right leg and inguinal lymph nodes with erosion on his right thigh and scrotum. Histological examination resulted in a diagnosis of Paget's disease. The patient was treated with radiation therapy for bilateral inguinal and pelvic lymph nodes, thoracolumbar spine metastasis. Paget's disease recurred on his scrotum one year later from his first visit, and he suddenly developed wheezing and dyspnea without any trigger. He was diagnosed with exacerbation of interstitial pneumonia based on the findings of diffuse ground-glass opacities on chest computed tomography. Despite corticosteroid therapy, he died of respiratory failure. We encountered a case of developing Paget's disease with lethal exacerbation of interstitial pneumonia. Because malignant neoplasms including Paget's disease commonly occur in elderly patients, we have to pay medical attention especially for lung lesions.[Skin Cancer (Japan) 2010 ; 25 : 29-32]
