Abstract
A 62-year-old male patient had noticed red eczema on the sole of his left foot about 10 years ago. Since 2 years ago, erosion and bleeding have repeatedly occurred at that site due to the patient's own scratching due to itching. He was diagnosed at another hospital with eczema and treated with steroid ointment without any remarkable effect. Then he was referred to our hospital. Physical examination revealed a red scratched erythema with erosion 11×12mm in size at that site. A diagnosis of eccrine poroma was diagnosed by skin biopsy, followed by total resection. The final pathological report resulted in eccrine poroma associated with Bowen disease, which were identified separately. Immunohistochemically, poroid cells had a positive reaction to anti-CEA antibody. Because coincidental occurrence of both disease entities is very rare, we thought there might be an interrelated immunological or biochemical correlation.[Skin Cancer (Japan) 2010 ; 25 : 181-184]