Abstract
A 55-year-old Japanese man with pigmented mammary Paget's disease (p-MPD) is reported. Physical examination revealed a 50×45 mm, blackish tumor with ulceration. Dermoscopic diagnosis of p-MPD is difficult because it usually shows a nonspecific pattern. Histopathology of the lesion disclosed intraepidermal and dermal atypical cells forming small clusters and underlying intraductal carcinoma. The tumor cells were positive for cytokeratin7, estrogen receptor, progesterone receptor, but negative for S-100 protein, melan-A and HMB-45. Paget's disease of the breast is usually non pigmented and occurs almost exclusively in women. P-MPD of the male is extremely rare.[Skin Cancer (Japan) 2012 ; 27 : 98-101]
