Abstract
The cases of 82 patients with extrmammary Paget's disease treated at the Department of Dermatology at Jichi Medical University Hospital between 1999 and 2010 were statistically studied. The average age was 71.4 years old, and the male/female ratio was 1.8 : 1. Seventy patients had lesions on the genital area. Six patients had lesions on the axilla, and two patients each had lesions on the abdomen or perianal area. 8.5% of the patients studied had lymph node metastases. All of them had invasive primary lesions. 4.1% of the patients showed local recurrence, and the primary lesions of all of the patients were in situ. The five-year survival rate of the patients was 100%, 65% and 0% with no, unilateral or bilateral lymph node metastases, respectively. The five-year survival rate of stages 1, 2, 3 and 4 was 100%, 100%, 75% and 0%, respectively. Both of the survival curves were very similar. Therefore, it seems that the prognosis of extramammary Paget's disease is strongly related with the existence of lymph node metastasis.[Skin Cancer (Japan) 2012 ; 27 : 179-185]
