A case of proliferative nodule arising within a giant congenital pigmented nevus

Abstract

A 22-year-old woman presented with a nodule within a giant congenital nevus on her back. A hisitopathological examination revealed the smooth transition of the pre-existing lesion and the nodule, the absence of strong atypical nuclei, the atypical mitotic figures and the absence of necrosis. Immunohistochemical stains showed only 7% labeling index with Ki-67. Based on observation, a diagnosis of proliferative nodule arising within a giant congenital pigmented nevus was made. One year and six months passed after the resection, but neither recurrence nor metastasis has occurred.[Skin Cancer (Japan) 2013 ; 28 : 264-267]