Abstract
A 75-year old woman noted a subcutaneous nodule on the left axilla in December, 2007. On February 29, 2012, physical examination revealed a subcutaneous nodule, 12×7mm in size, with a pedunculated tumor, 3×2mm, on the left axilla. Excisional biopsy was performed on March 6, 2012. Histologically, the neoplasm consisted of nests with atypical epithelial cells and glands with abundant eosinophilic cytoplasm that showed decapitation secretion. Normal mammary glands or ducts were not found. Immunohistochemistry showed that tumor cells were positive for EMA, CK7 and GCDFP-15, but negative for CEA, S-100, ER, PR or HER-2. This tumor was diagnosed as primary cutaneous apocrine carcinoma. A wide excision with left axillar lymph node dissection was performed on April 6, 2012. There has been no evidence of recurrence or metastasis for fifteen months, after the last surgery.[Skin Cancer (Japan) 2013 ; 28 : 297-301]
