Abstract
A 22-year-old woman noticed a nodule on the left side of her scalp ten years ago, and it had been increasing in size. It was resected at a nearby hospital in January 2013. Histopathological examination showed a single nodule with central denaturation of the collagen fiber at a lower magnification. Tumor cells were composed of a mixed proliferation of eosinophilic epithelioid cells and spindle cells, together with intercellular collagen deposition at a higher magnification. Immunohistochemical examination showed the tumor cells were positive for AE1/AE3, EMA, and CD34, and negative for smooth muscle actin, desmin, and S-100 protein, and characteristically negative for INI1protein. That result provided a diagnosis of distal type of epithelioid sarcoma.[Skin Cancer (Japan) 2014 ; 29 : 176-180]
