Abstract
An 81-year-old Japanese woman developed a subcutaneous tumor measuring approximately 5.5 × 4.4 cm located close to the upper region of a gynecological surgical wound in the abdominal wall. She underwent uterine resection for suspected uterine myoma at a gynecological clinic 7 years prior. Specimens of the tumor showed several nests of oval or spindle-shaped cells with mild cytologic atypia accompanied by a number of small vessels. In an immunohistochemical examination, the tumor cells tested positive for vimentin, CD10, estrogen receptor, and progesterone receptor. We diagnosed the subcutaneous tumor as endometrial stromal sarcoma (ESS) recurrence originating from the primary uterine ESS, because the investigated specimens of the uterine body excised in the clinic had similar nests of cells observed in the present subcutaneous tumor. Dermatologists should consider the possibility of ESS in the differential diagnosis of a subcutaneous tumor, especially in patients with a history of gynecological disease.[Skin Cancer (Japan) 2015 ; 30 : 102-107]
