Abstract
A 40-year-old woman noticed a tumor on her left shoulder 2 month previously. As the tumor enlarged rapidly, she was referred to our hospital. The tumor was 60 mm in diameter at her first visit. Histological findings revealed proliferation of spindle cells with myxoid tissue. The tumor also contained highly cellular lesions with numerous atypical cells. We diagnosed this tumor as a high-grade myxofibrosarcoma. The patient underwent wide resection with 30-mm safety margins. Five months after extended resection, a 6-mm solitary nodule was found in the left upper lung lobe on both computed tomography and positron-emission tomography. Partial resection of the left upper lobe was performed, and the nodule presented with the same histological findings as the primary cutaneous lesion. Currently, 2 years since she underwent the partial resection, no local recurrence or distant metastasis has been detected. Physicians should pay attention to not only local recurrences, but also distant metastases, when they examine patients with myxofibrosarcoma.[Skin Cancer (Japan) 2016 ; 31 : 35-39]
