2016 Volume 31 Issue 2 Pages 110-113
Pseudoprogression is an atypical response after cancer treatment, and is defined as a temporary increase in the total tumor burden. Previously, pseudoprogression has often been reported after combination treatment of chemotherapy and radiotherapy, but recently, it has been reported after immune checkpoint blockade therapy, such as after treatment with the PD-1 inhibitor nivolumab. Pseudoprogression is shown as nodules on computed tomography (CT) imaging, which indicates T cell infiltration and extensive necrosis. In our study, we explored pseudoprogression in 8 malignant melanoma patients using 18F-FDG PET/CT imaging in our department.[Skin Cancer (Japan) 2016 ; 31 : 110-113]
