Two cases of advanced basal cell carcinoma treated with cisplatin and adriamycin followed by carboplatin and adriamycin

Abstract

Case 1 : A 51-year-old man, who underwent resection of basal cell carcinoma in his lower abdomen 11 years ago, noticed edema of his left leg last year. Computed tomography scans revealed metastasis in his lungs, left inguinal lymph nodes, and left ilium. The number of nodules on his scrotum gradually increased. Case 2 : A 64-year-old woman underwent an operation for basal cell carcinoma on her right foot, and right inguinal lymph metastases were removed 4 years later. Nine and a half years after the primary visit, her chest X-ray scan showed multiple lung nodules. Mediastinal, periaortic, and right external iliac lymph metastasis were also found. Both cases were treated with cisplatin and adriamycin, and gained partial response. However, due to renal impairment, treatments were changed to carboplatin and adriamycin. Partial response was maintained in case 1, but in case 2, the disease progressed and the patient died.[Skin Cancer (Japan) 2017 ; 32 : 44-50]