2017 Volume 32 Issue 2 Pages 197-201
Combination therapy using cetuximab and radiotherapy is a promising treatment option for the management of locally advanced head and neck squamous cell carcinoma (SCC). Moreover, some reports have shown that the treatment of unresectable cutaneous SCC in combination with radiotherapy is also effective. We report three cases of cutaneous SCC treated with cetuximab and radiotherapy. Patients were initially administered cetuximab at a loading dose of 400 mg/m2, followed by administration of weekly infusions of 250 mg/m2 during radiotherapy. One patient achieved complete response and two patients did partial response. No patient demonstrated adverse effects over Grade 3. We suggest that combination therapy using cetuximab and radiotherapy is potentially useful for the management of unresectable cutaneous SCC.[Skin Cancer (Japan) 2017 ; 32 : 197-201]
