2018 Volume 33 Issue 1 Pages 35-39
A 50-year-old woman developed myoepithelioma in the pubic region. A nodular tumor approximately 7 cm in size along the longest dimension was located on the subcutaneous tissue with no adhesion to the surrounding structures. On microscopic examination, sections showed proliferation of epithelioid- to spindled-shaped cells arranged in a cord-like and small nested pattern, on a background of myxoid and fibrous stroma. Immunohistochemically, the tumor cells were positive for epithelial membrane antigen, α-smooth muscle actin, and negative for S-100, desmin, and pan-cytokeratin. The tumor was excised with negative margins and there was no recurrence or metastasis after the 2-year follow-up. [Skin Cancer (Japan) 2018 ; 33 : 35-39]