Skin Cancer
Online ISSN : 1884-3549
Print ISSN : 0915-3535
ISSN-L : 0915-3535
Extramammary Paget’s disease associated with brain metastasis : a case report
Naohisa ICHIKIHirofumi NIWAKanako MATSUYAMATakaaki ITAZUNoriyuki NAKAYAMAMariko SEISHIMA
Author information
JOURNAL RESTRICTED ACCESS

2020 Volume 35 Issue 2 Pages 71-75

Details
Abstract

A 74-year-old man presented with an enlarging erythema on the right scrotum for 4 years. Based on histopathological findings, we diagnosed the patient with extramammary Paget’s disease (EMPD). After 4.5 years, right inguinal lymphadenopathy was detected, and lymphadenectomy was performed. In addition, radiotherapy was performed in the right external iliac and common iliac regions. After 8.5 years, lymphadenopathy was observed at the left clavicle, posterior diaphragmatic leg, and abdominal aorta, and one month later, the patient developed muscle weakness and numbness. For suspected brain metastasis of EMPD, we resected the region and provided postoperative irradiation. Nevertheless, the number of brain metastases increased, and the patient received additional whole-brain irradiation.

There have been a few reports of EMPD brain metastases. Particularly, this case is considered to be rare since metastases did not occur in other major organs.[Skin Cancer (Japan) 2020 ; 35 : 71-75]

Content from these authors
© 2020 The Japanese Skin Cancer Society
Previous article Next article
feedback
Top