A case of squamous cell carcinoma of unknown primary lesion with inguinal lymph node metastasis
2021 Volume 36 Issue 1 Pages 21-25
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2021 Volume 36 Issue 1 Pages 21-25
An 81-year-old man noticed a subcutaneous mass in his left groin on May, 20XX. He had no previous history of malignancy. The left inguinal lymph nodes were swollen, and positron emission tomography-computed tomography showed an accumulation of fluorodeoxyglucose.
Histopathological examination of the resected lymph node revealed lymph node metastasis of a well-differentiated squamous cell carcinoma (SCC). No primary lesion was found after systemic physical examinations. The diagnosis of inguinal lymph node metastasis of SCC of unknown primary lesion was made. An additional inguinal lymph node dissection was performed. There have been no signs of recurrence or metastasis to other organs for 17 months after the surgery.
Cancers of unknown primary lesions account for 1-5% of malignant tumors. Of these, SCC is extremely rare. Metastatic cancers of unknown primary lesions usually have a poor prognosis ; however, SCC has been reported to have a relatively good prognosis. Although it is very rare, patients with such malignancies should be followed up closely.[Skin Cancer (Japan) 2021 ; 36 : 21-25]
