2023 Volume 38 Issue 1 Pages 7-11
A 72－year－old male noticed a tumor on the left upper back approximately 7 months before his referral to our hospital, which grew rapidly. A 20 cm oval, elastic, and soft mass with moist and uneven surface and satellite lesions was observed during his visit to our hospital. Lymphadenopathy was observed in both axillae. The skin biopsy revealed trabecular proliferation of squamoid atypical keratinocytes. Computed tomography showed multiple lymphadenopathies in the mediastinum and multiple liver metastases. The day following his admission, disorientation and dysarthria were observed, and magnetic resonance imaging revealed multiple cerebral infarctions. He was diagnosed with Trousseau syndrome ; treatment with dalteparin sodium resulted in recovery without paralysis. The dorsal mass and swollen lymph nodes in both axillae were dissected as palliative care, followed by chemotherapy with carboplatin and epirubicin. After the first course of chemotherapy, he died of gastrointestinal bleeding. [Skin Cancer (Japan) 2023 ; 38 : 7－11]
