A case of multiple squamous cell carcinoma and Bowen’s disease complicated by Fanconi anemia : a case report

Abstract

Here, we present the case of multiple squamous cell carcinoma (SCC) and Bowen’s disease in a 32－year－old man who was diagnosed with FA at the age of 6. Over the past eight years, five skin tumors have been confirmed, with two occurring on the genital skin, one on the abdominal skin, and two on the occipital area. The tumors ranged from 4－18 mm in diameter and exhibited various appearances, including red lesions, black lesions, elevations, and ulcers. Each tumor was resected with a margin. Pathological examination showed three SCC and two Bowen’s disease. In Japan, while there have been 13 reports involving 17 cases of SCC in patients with FA, our case presents the first report of SCC occurring on the skin of this population, emphasizing its importance.[Skin Cancer (Japan) 2024 ; 39 : 204－213]