Abstract
The case was a 38 year-old male who had a subcutaneous nodule on his left axillarregion. There was no malignant sign with computed tomography, Ga scintigraphy, and endoscopy. Histopathologically, the tumor consisted of atypical tumor cellsthroughout the dermis and subcutaneous fat and partially showed tubular pattern. Inimmunohistochemical study, tumor cells showed EMA (+), cytokeratin10 (+), cytokeratin19 (+), WGA (+), RCA-1 (+), ConA (+), S-100 (-), α1-antitrypsin (-), α1-antichymotrypsin (-), lysozome (-), desmin (-), LCA (-), and PSA (-) . Furthermore, tumor cells revealed high PCNA labeling index and a remarkable increase of FINORs not only in number but also in volume which were compatible with malignant tumor. On ultrastructual examination, there were desmosome like structure and tubular likestructure with microvilli between tumor cells. From these results, we diagnosed this case as primary malignant tumor with sweat gland differentiation.
