Abstract

We already reported this case as a malignant hemangioendothelioma (MHE) case where effects of one shot intraarterial recombinant interleukin-2 (IL-2) injection therapy were remarkable compared to conventional local injection of IL-2 or intraarterial therapy. We first used thermography to observe the therapy course of this case. The patient was 77-year-old female with MHE at the left forehead. At the first examination, tumor region and its circumferential erythema demonstrated high temperature on thermography. After one shot intraarterial IL-2 injection for 17 times, high temperature region on thermography was markedly reduced and the erythema disappeared. Pathological finding of the region revealed no tumor cells. Since thermography could detect aggravation of the disease due to discontinuance of thetherapy at an early stage as enlargement of the high temperature region, the method was estimated valuable asasupplemental diagnostic method for observation of the disease course.