Abstract

We reported a case of 24 year-old office girl patient with Bowen's disease occurring on her right fourth finger. Histological findings were mild atypical feature for the diagnosis of Bowen's disease. We found no evidence of human papilloma virus (HPV) in this case by methods of immunohistochemistry, southern blot hybridization, and electon microscopy.
Of 6 patients with Bowen's disease developed on fingers who visited to our clinic in the period from July 1974 to March 1996, we recognized the HPV antigen in 2 cases by the PAP method. It is possible that the etiology of Bowen's disease on fingers is related to HPV infection.