Abstract

We reported two cases of malignant hemangioendothelioma (MHE) . Case 1 was a 84-year-old female patient who had dark red or purple plaque, 18×14mm in diameter on her parietal region. The lesion was excised, and recombinant interleukin 2 (rIL-2) applied topically. At 15 months after the operation, she expired due to lung metastases. Case 2 was a 78-year-old male patient who had palm-sized dark red plaque with several nodules and ulcers. In spite of combination of wide resection and topical rIL-2 injectiion, he expired 2 months later.