Abstract

We describe A 81-year-old woman with spindle cell squamous cell carcinoma (SCC) on the head, which arouse from old burn scars existing for 73 years. The tumor was an ulcerated nodule measuring 2.7×1.8×1.1cm in size. The tumor was surgically excised with a 1.5cm safety margin under general anesthesia. Histologically, the tumor was composed of atypical spindle cells which arranged in a storiform pattern. However, a direct transition from squamoid cells to spindle cells was observed. Immunohistochemical study revealed the positive expression of epithelial membrane antigen, keratin and involucrin in the squamoid cells. In contrast, involucrin was weakly positive in spindle cells.