Abstract
We report a case of melanoma on the head of a 48-year-old female. She had noticed a nodule on her head 4 years before her first visit of our hospital. Another rapidly growing pedunculated nodule developed near the first one 2 months before.
The tumor accompanied pigmented macule, 78×48mm in size. Histologically, two large tumor mass were composed with atypical tumor cells with melanin granules. Tumor cells, scattered in the epidermis, showed Pagetoid phenomenon and invaded into many hair follicles. Tumor cells completely ocupied some hair follicules but do not invaded into the dermis around the fibrous root sheath. The diagnosis was superficial spreading malignant melanoma (pT4aN0M0, Breslow's thickness 13mm, Stage III). Wide local exicison with neck dissection and three course of chemotherapy (DTIC, ACNU, VCR, IFN-beta) were performed. The patient showed no evidence of recurence for 10 months after the operation. [Skin Cancer (Japan) 2000; 15: 236-239]
