Abstract
se of drug eruption after long term rIL-2 therapy is reported.
A 67-year-old man had a tumor on his right temporal scalp on June 1995. On April 1996, the lesion was excised and the raw surface was covered with grafted skin at another hospital. Histopathological findings were similar to malignant hemangioendothelioma. On May 1996, so he visited to our department to begin the combination therapy of rIL-2, operation, radiation.
The rIL-2 therapy with celmoleukin had been started by local injection, one shot arterial injection since May 1996. But on June 1998, edematous, irregular, erythema was observed on the medial aspects of his upper arms and thighs. We suspected drug eruptions which were caused by celmoleukin. So we continued rIL-2 therapy with teceleukin by one shot arterial injection. On May 1999, the similar eruptions were observed again. We suspected drug eruptions which were caused by teceleukin.
Erythema is well known as one of the side effects of rIL-2. But this is conc eivable as a rare case of drug eruption after long term rIL-2 therapy. [Skin Cancer (Japan) 2000; 15 : 280-283]
