Abstract
The first choice of treatment for squamous cell carcinoma is surgical excision, then other choices are radiation therapy and chemotherapy. Recently, it is chosen for treatment of squamous cell carcinoma that biological response modifier (-for example- Interferon, Interleukin-1, Interleukin-2, tumor necrotizing factor), cryosurgery, chemical surgery, electrosurgery, local chemotherapy and thermal therapy is go on. But progressive case has various problems for treatment -for example- high ages, informed consent and quality of life. We experienced a case of progressive squamous cell carcinoma which had recurrence and metastasis for 5 years. This case was finally treated with Retinoid and got complete remission. It is reported that Retinoid is effective drug to inhibit tumor growth, and we recognized that Retinoid inhibited tumor growth in this case. We think that Retinoid has a possibility of one of treatment for squamous cell carcinoma. [Skin Cancer(Japan) 2000; 15: 289-294]
