Abstract
Dermatofibrosarcoma protuberans (DFSP) are uncommon skin tumors that have a high incidence of local recurrence even with wide surgical margin, but DFSP rarely metastasize. We report a case of DFSP that showed accelerated growth during pregnancy.
Immunohistochemical stains for CD34, S-100 protein, factor XIIIa, and estrogen and progesterone receptors were performed on biopsy specimens. Previous reports showed expression of progesterone and PDGF receptor which may be factors that accounts for their accelerated growth during pregnancy. [Skin Cancer (Japan) 2002; 17: 51-53]