A case of fibrosarcomatous variant of dermatofibrosarcoma protuberans

Abstract

A 43-year-old Japanese woman visited our hospital with a large tumor on her back. The tumor size was 20×15×4cm. She first noted the tumor on her back 5 years ago. Wide excision of the tumor including fascia and skin grafting were performed. Histologically, the tumor consisted of areas of ordinary dermato-fibrosarcoma protuberans composed of spindle-shaped tumor cells with storiform patterns. In other areas, a dense proliferation of atypical spindle cells arranged in fascicular and herring-bone patterns was obserbed. Immunohistochemical staining of CD34 showed strongly positive in DFSP and showed decreased CD34 reactivity in fibrosarcoma.
No local recurrence and metastasis was seen under the follow-up period of 7 months. [Skin Cancer (Japan) 2002; 17: 57-60]