Abstract
We reported an 81-year-old man with primary cutaneous T-cell lymphoma with a gastrointestinal stromal tumor (GIST) . He manifestated a solitary reddish tumor on the left hip that grew rapidly to a size of 4 ×4×1cm during a period of two months. A skin biopsy of the tumor showed dense infiltration of abnormal lymphocytes in the dermis and subcutaneous tissue. The immunophenotype was positive for LCA and UCHL-1, and negative for L-26. An abdominal CT revealed a lesion of a large nodule on the outside of the stomach wall, that was diagnosed as a GIST with immunohistochemically CD-117+. 3 couses of combined chemotherapy (THP-COP; pirarubicin, cyclophosphamid, vincristin and prednizorone) were effective for cutaneous T-cell lymphoma.
A local excision of the GIST was performed, and he had no recurrence. There were no reports of cutaneous T-cell lymphoma with GIST. [Skin Cancer (Japan) 2002; 17: 94-97]
