Abstract
We report a 62-year-old woman with eccrine porocarcinoma on perianal skin. The patient noticed a red tumor on perianal skin 10 months before the first consultation, and the tumor size had been increased. On the first consultation, elastic hard tumor with 3×4×2 cm in size was observed on the left perianal lesion, 1.5 cm away from the anus, and 2 lymph nodes were palpable in the left inguinal lesion. A diagnosis of eccrine porocarcinoma was made based on the histological findings of biopsy specimens from the tumor and left inguinal lymph node. The tumor and left inguinal lymph nodes were resected and adjuvant chemotherapy with 3 courses of FECOM (CBDCA, EPIR, MMC, 5-FU, and VCR) was given. Although recurrence of the tumor and the metastasis were not observed during the therapy, multiple coin lesions were found in the lung by computed tomography 3 months after cessation of FECOM. The 3 additional courses of FECOM did not change the number and the sizes of metastatic lung lesions for 2 months. However, weekly therapy of docetaxel was given for the metastasis in the right inguinal lymph node. The result was a condition in which, due to the number and sizes of the metastatic lung lesions but, the therapy could not prevent metastasis to the left pubic bone. [Skin Cancer (Japan) 2005; 20: 301-305]
